bismuth subsalicylate intracellular

ACG Clinical Guideline: Diagnosis, Treatment, and ...

Bismuth subsalicylate. BSS has been shown in several studies to reduce the frequency of TD when used during period of risk for 3 weeks (207, 208, 209). While the salicylate portion of the drug provides antidiarrheal effects, it is the bismuth moiety that is active when the molecule is used for chemoprophylaxis .

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Dulaglutide | DrugBank Online

Apr 29, 2015· Dulaglutide increases intracellular cyclic AMP (cAMP) in beta cells leading to glucose-dependent insulin release. Dulaglutide also decreases glucagon secretion and slows gastric emptying. ... Bismuth subsalicylate: Bismuth subsalicylate may increase the hypoglycemic activities of Dulaglutide.

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Clarithromycin 500mg Tablets - Summary of Product ...

Apr 14, 2021· Clarithromycin is an antibiotic belonging to the macrolide antibiotic group. It exerts its antibacterial action by selectively binding to the 50s ribosomal subunit of susceptible bacteria preventing translocation of activated amino acids. It inhibits the intracellular protein synthesis of …

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Pathogenic Bacteria and Identification - Microbiology ...

Bismuth subsalicylate (Pepto-Bismol) kingella kingae: Kingella kingae is part of the HACEK group of bacteria. It is Gram-negative, coccobacilli, associated with septic arthritis, osteomyelitis, spondylodiscitis, bacteremia, meningitis, lower respiratory infection, and endocarditis. ... It is referred to as a facultative intracellular microbe ...

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Association between Brachyspira and irritable bowel ...

Objective The incidence of IBS increases following enteric infections, suggesting a causative role for microbial imbalance. However, analyses of faecal microbiota have not demonstrated consistent alterations. Here, we used metaproteomics to investigate potential associations between mucus-resident microbiota and IBS symptoms. Design Mucus samples were prospectively collected from sigmoid …

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Pylera Capsules (Bismuth Subcitrate Potassium): Uses ...

Mar 19, 2021· Bismuth subsalicylate did not show mutagenic potential in the NTP Salmonella plate assay. ... mechanism of action in an anaerobic environment is not fully understood but a possible mechanism includes reduction by intracellular electron transport proteins after entry into the organism. Because of this alteration to the metronidazole molecule, a ...

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Doxycycline in the management of sexually transmitted ...

Doxycycline is a second-generation tetracycline, available worldwide for half a century. It is an inexpensive broad-spectrum antimicrobial agent largely used in the management of several bacterial infections, particularly involving intracellular pathogens, as well as in the treatment of acne or for the prophylaxis of malaria.

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Tetracycline | DrugBank Online

Jun 13, 2005· Additionally tetracycline may alter the cytoplasmic membrane of bacteria causing leakage of intracellular contents, such as nucleotides, from the cell. ... Bismuth subsalicylate: The serum concentration of Tetracycline can be decreased when it is combined with Bismuth subsalicylate.

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Diarrheagenic Escherichia coli - Clinical Microbiology Reviews

SUMMARY Escherichia coli is the predominant nonpathogenic facultative flora of the human intestine. Some E. coli strains, however, have developed the ability to cause disease of the gastrointestinal, urinary, or central nervous system in even the most robust human hosts. Diarrheagenic strains of E. coli can be divided into at least six different categories with corresponding distinct ...

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Managing Acute Gastroenteritis Among Children: Oral ...

Bismuth subsalicylate has limited efficacy in treating traveler''s diarrhea (68) and other causes of acute gastroenteritis among children (69). Although the side effects are fewer than those from antimotility agents, certain theoretical concerns regarding the potential toxicity from salicylate absorption remain ( 70 ), and trials supporting its ...

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Bacterial Infections of the Gastrointestinal Tract ...

Shigellosis (Bacillary Dysentery) When gastrointestinal illness is associated with the rod-shaped, gram-negative bacterium Shigella, it is called bacillary dysentery, or shigellosis fections can be caused by S. dysenteriae, S. flexneri, S. boydii, and/or S. sonnei that colonize the GI tract. Shigellosis can be spread from hand to mouth or through contaminated food and water.

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Pathogenesis of Helicobacter pylori Infection | Clinical ...

SUMMARY Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the most successful human pathogens, as over half of the world''s population is colonized with this gram-negative bacterium. Unless treated, colonization usually persists lifelong. H. pylori infection represents a key factor in the etiology of various gastrointestinal diseases, ranging from chronic ...

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Doxycycline (Professional Patient Advice) - Drugs

Jun 09, 2020· Bismuth Subsalicylate: May decrease the serum concentration of Tetracyclines. Management: Consider dosing tetracyclines 2 hours before or 6 hours after bismuth. The need to separate doses during Helicobacter pylori eradication regimens is questionable. Consider therapy modification. Calcium Salts: May decrease the serum concentration of ...

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285125-02-2 | Sigma-Aldrich

Feb 02, 2002· Search results for 285125-02-2 at Sigma-Aldrich. Compare Products: Select up to 4 products. *Please select more than one item to compare

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Helicobacter pylori - Wikipedia

Helicobacter pylori, previously known as Campylobacter pylori, is a gram-negative, microaerophilic, spiral (helical) bacterium usually found in the stomach. Its helical shape (from which the genus name, helicobacter, derives) is thought to have evolved in order to penetrate the mucoid lining of the stomach and thereby establish infection. The bacterium was first identified in 1982 by ...

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Tetracycline | C22H24N2O8 - PubChem

Tetracycline is a broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium Streptomyces aureofaciens bacteria, tetracycline binds to the 30S ribosomal subunit, interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis.

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Salicylic acid - Wikipedia

Bismuth subsalicylate, a salt of bismuth and salicylic acid, is the active ingredient in stomach-relief aids such as Pepto-Bismol, is the main ingredient of Kaopectate, and "displays anti-inflammatory action (due to salicylic acid) and also acts as an antacid and mild antibiotic".

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Resveratrol | DrugBank Online

Resveratrol (3,5,4''-trihydroxystilbene) is a polyphenolic phytoalexin. It is a stilbenoid, a derivate of stilbene, and is produced in plants with the help of the enzyme stilbene synthase. It exists as...

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